Application and preparation of sodium metabisulfite

Sodium metabisulfite is white or yellow crystalline powder or small crystal, with strong SO2 smell, specific gravity 1.4, soluble in water, aqueous solution is acidic, SO2 is released upon contact with strong acid to generate corresponding salts, and if left in the air for a long time, it will oxidize Into Na2S2O6, so the product cannot last for long. Above 150 degrees Celsius, SO2 is decomposed.

Sodium metabisulfite is also known as heavy sulfoxide, also known as sodium metabisulfite, or sodium disulfite. It is a white or slightly yellow crystalline powder with a relative density of 1.4. It is soluble in water and glycerin, slightly soluble in ethanol, and insoluble in benzene. Its solubility in water increases with increasing temperature. It is 54g/100mL water at 20℃ and 81.7g/100mL water at 100℃. The aqueous solution is acidic. After dissolving in water, it generates stable sodium ammonium sulfite, which is easily affected by moisture. Decompose, easily oxidize slowly in exposed air and emit SO2, and finally absorb oxygen to be oxidized; contact with strong acid to emit SO2, and generate corresponding salts; generate sodium sulfite when reacting with caustic soda or soda ash solution; can form adduct with aldehydes . The allowable content of sodium metabisulfite in the air is 5mg, and the intake of toxic sodium metabisulfite products are classified into industrial grade and food grade, and their quality indicators are different.

Industrial grade sodium metabisulfite is widely used. Used for purification of chloroform, phenylpropyl sulfone and benzaldehyde in the pharmaceutical industry; used as a coagulant in the rubber industry; used as a dechlorinating agent for cotton bleaching, cotton cloth smelting aid and mordant for printing and dyeing in the printing and dyeing industry; for the leather industry Used in leather processing, it can make leather soft, plump and tough, with waterproof, flexural, abrasion resistance and other properties; used in the chemical industry for the production of hydroxyvanillin, hydroxylamine hydrochloride, etc.; used in the photosensitive industry as a developer.

If there is research and development of a method for manufacturing sodium metabisulfite feed antifungal agent, which includes the following steps:

A. Steps for extracting andrographis paniculata extract, wash andrographis paniculata and put it in a glass container, and then put 95% ethanol solution with a mass percentage concentration in the glass container, after soaking for 3 hours, put the glass container in water and bath in 60 degree Celsius for 10 hours , Filter out the drug solution; the glass container filled with the drug residue is then placed in water at 60 degrees Celsius for 10 hours, and then the drug solution is filtered out to obtain the andrographis paniculata extract;

B. The steps of extracting Didi extract:

C. Mix sodium metabisulfite and dehydroacetic acid with the andrographis paniculata extract obtained in step A and the dianthus extract obtained in step B at a mixing temperature of 35 degrees Celsius;

D. Mix the mixture of step C with astragalus polysaccharides and tea polyphenols at room temperature, and stir evenly to obtain the sodium metabisulfite feed mold inhibitor.

The manufacturing method of the invention is simple, the prepared product has a simple ratio, is convenient to use, has low residue, and keeps the nutritional balance of the feed. There is also research and development of a stabilized injectable pharmaceutical composition of epinephrine and its salts, which contains sodium metabisulfite, and the ratio of epinephrine and its salts to sodium metabisulfite in the composition ranges from about 1:0.005 to about 1:1.5 (By weight). It has been observed that a stable injectable epinephrine composition with excellent storage stability and substantially no excess can be prepared by using sodium metabisulfite in the stated ratio. Specifically, it was found that the use of sodium metabisulfite in the stated ratio controlled the level of adrenaline sulfonate impurities in the pharmaceutical composition.

Food grade sodium metabisulfite can be used as bleaching agent and leavening agent for biscuits and cakes, nutrient retention agent for dehydration of vegetables, preservative for storing fruits, sterilization preservative for brewing and beverages, etc.

If there is research and development of a vegetable preservative containing sodium metabisulfite, including the following parts by weight of each component: sodium metabisulfite 30-40 parts, ethephon 5-10 parts, peroxycalcium calcium 20-30 parts, ethylene glycol 1-5 parts, borax 5-9 parts, benzene polyphenol 5-10 parts, hydroxytetrahydropyrimidine 2-4 parts. Preferably, the preservative includes the following parts by weight of each component: sodium metabisulfite 32-38 parts, ethephon 6-9 parts, peroxycalcium calcium 23-28 parts, ethylene glycol 1.5-4.5 parts, borax 5.8- 8.3 parts, benzene polyphenols 5.8-9.6 parts, hydroxytetrahydropyrimidine 2.3-3.4 parts. The technical problem to be solved by the present invention is to provide a vegetable preservative, which can effectively inhibit the growth of mold, reduce the evaporation of water, extend the shelf life, and be safe and environmentally friendly.